What's it do for me?

FrapCalc analyzes FRAP curves to quantitatively estimate parameters of protein dynamics.


  • Import FRAP measurement tab-delimited text files of Zeiss data format (6 different data structures)
  • Leica data format (7 different data structures) - Three different ways of normalizing FRAP curve - Curve fitting by single and double exponential formula and 2 diffusion formula. Correction for the acquisition bleaching.
  • Output of half-max, diffusion coefficient, mobile/immobile fractions.
  • Weighting for the fitting.
  • Evaluation of goodness of fit by chi-square and gamma function.
  • Graphing of the fitted curve and estimation curve without acquisition bleaching.
  • Batch Fitting
Created by

K Miura

Is it open source?