The Center for Open Bioimage Analysis (COBA) was established in 2020 with a P41 grant from the NIH National Institute of General Medical Sciences to Co-PIs Carpenter (Broad) and Eliceiri (UW-Madison). As a National Biomedical Technology Research Resource, our purpose is to develop and disseminate novel technologies throughout the biomedical research community. COBA’s mission is to serve the cell biology community’s growing need for sophisticated software for light microscopy image analysis.